Pre-implantation Genetic Testing

In the rapidly advancing field of reproductive medicine, Pre-implantation Genetic Testing (PGT) has emerged as one of the most groundbreaking advancements. This cutting-edge technique is used alongside In Vitro Fertilization (IVF) to screen embryos for specific genetic conditions before they are implanted into the uterus. At Avira Fertility Hospital, we provide the most advanced PGT services, ensuring comprehensive care under one roof.

What is Pre-implantation Genetic Testing?

PGT involves genetic testing of embryos produced through IVF to identify any abnormalities before implantation. The testing can be performed for several reasons, including:

• PGT-A (for aneuploidies): Screening embryos to ensure the correct number of chromosomes, reducing the chances of chromosomal abnormalities.
• PGT-M (for monogenic/single gene defects): Detecting known inherited genetic disorders, such as cystic fibrosis or Huntington’s disease.
• PGT-SR (for structural rearrangements): Testing for chromosomal rearrangements that could lead to miscarriage or genetic disorders.

Benefits of Pre-implantation Genetic Testing:

• Increased Pregnancy Success: PGT ensures only embryos without specific genetic abnormalities are transferred, enhancing the chances of a successful pregnancy.
• Reduced Risk of Genetic Disorders: Parents carrying inherited genetic conditions can significantly reduce the risk of passing these on to their children.
• Lower Miscarriage Rates: By identifying chromosomal abnormalities, PGT lowers the risk of miscarriage and pregnancy loss.

At Avira Fertility Hospital, we uphold the highest standards of care to help you maximize the benefits of PGT, providing advanced diagnostics and personalized treatment plans.

Considerations for PGT:

Though PGT offers many benefits, there are important medical and ethical considerations:

• False Positives/Negatives: Like all tests, PGT is not foolproof. In rare cases, it may yield false results, potentially leading to viable embryos being discarded or affected ones being implanted.
• Ethical Concerns: Selecting embryos based on genetic characteristics can raise ethical questions, such as concerns over “designer babies” or the implications of embryo selection.
• Cost: PGT adds to the cost of IVF, which is something couples need to consider when opting for this procedure.